Colorectal Cancer Frequently Asked Questions

Precision medicine, also called personalized medicine, allows your oncology team to create a plan tailored specifically to the molecular makeup of the tumor. Our oncologists analyze the biomarker test results that identify genetic changes, proteins, or other characteristics that may respond to targeted therapies or immunotherapy. These treatments are designed to attack specific features of the colorectal cancer while minimizing damage to healthy cells. If biomarker testing does not identify abnormal changes, your oncologist will recommend other treatment options that may be appropriate for you.

Our blog explains more about how biomarker testing impacts colorectal cancer treatment.

Colorectal cancer often begins as a polyp, which is a growth that develops in the lining of the colon or rectum. While many polyps never become cancerous, some can develop into cancer after some time. Learn more about the cause of colon polyps.

When colorectal cancer starts to spread, it will first grow deeper into the wall of the colon or rectum. When it spreads, or metastasizes, it will usually reach nearby lymph nodes in the groin first, followed by the liver and the lungs. In some cases, it may also spread to the lining of the abdomen (peritoneum), bones, or, less frequently, the brain.

The location and extent of the colorectal cancer spread help determine the most appropriate treatment approach. If the tumor is large or has spread beyond the colon at the time of diagnosis, surgery may not be the first step. Other treatments may be recommended before surgery to shrink or control the cancer.

Only about 5-10% of colorectal cancer cases are hereditary. They are linked to conditions such as Lynch syndrome or familial adenomatous polyposis (FAP). Learn about the genetics of colorectal cancer.

A family history of colorectal cancer or certain related cancers, including endometrial, ovarian, or stomach cancer, can increase your risk. Other colorectal cancer risk factors, including acquired (somatic) genetic changes, certain digestive conditions such as ulcerative colitis, and lifestyle habits, may also play a role.

If you are concerned about your family history, our genetic counselors can help assess your risk and determine whether genetic testing may be beneficial. Understanding your colorectal cancer risk can help you make informed choices about your health, including when to start screening. Learn about Genetic Risk Education at Affiliated Oncologists. For individuals with a family history of colorectal cancer, early and regular screening is especially important.

Learn more in our blog: When Should You Start Colon & Rectal Cancer Screening?

Every patient’s experience is unique, and side effects depend on the treatments you receive and how your body responds.

Some common side effects of colorectal cancer treatment may include:

• Fatigue

• Nausea and vomiting

• Changes in appetite or taste

Certain chemotherapy regimens, such as FOLFOX, can cause increased sensitivity to cold or heat, particularly in the hands and feet, called neuropathy. To learn more about the possible side effects of FOLFOX, read our blog.

At Affiliated Oncologists, our supportive care team works closely with patients to help prevent, manage, and reduce treatment-related side effects whenever possible. Be sure to keep your care team informed about how you’re feeling so they can give you the support you need.

Learn more about common cancer treatment side effects and how to manage them.

The specific combination of chemotherapy drugs will determine if hair loss is more likely for you. Complete hair loss is less likely with the FOLFOX chemo combination used for colorectal cancer, although you may experience hair thinning. Patients who receive FOLFIRI may experience hair loss due to the drug irinotecan.

If you have concerns about changes to your hair or any other side effects, talk with your oncologist, advanced practice provider, or oncology nurse. Our team can offer supportive resources to help you feel more comfortable.

Learn more about managing hair loss as a side effect of cancer treatment.

Affiliated Oncologists has provided expert cancer care to patients throughout the South Chicago area for over 50 years. Our board-certified cancer specialists have extensive experience diagnosing and treating colorectal cancer using the most advanced technologies and treatments available.

Your colorectal cancer care is led by a multidisciplinary team that may include a medical oncologist, radiation oncologist, oncology nurses, and supportive care specialists. Together, they develop the best treatment plan for each patient and ensure you receive comprehensive, compassionate care close to home. Meet the colorectal cancer team at Affiliated Oncologists.

Understanding the financial aspects of cancer treatment is an important part of your care. At Affiliated Oncologists, our patient financial counselors will review your insurance coverage, explain what services are covered, and help you understand what out-of-pocket costs you may expect before treatment begins.

As an independent oncology practice, Affiliated Oncologists is often able to provide cancer care at a lower overall cost than hospital outpatient departments. According to the Community Oncology Alliance, cancer treatment can cost up to 50% less at an independent cancer center than in a hospital-based setting.

Our goal is to help you receive the highest quality cancer care while minimizing the financial impact of treatment whenever possible.

Learn more about the difference in costs between a hospital-based outpatient cancer center and a community-based cancer center like Affiliated Oncologists.